Effect of the Deletion of Genes Encoding Proteins of the Extracellular Virion Form of Vaccinia Virus on Vaccine Immunogenicity and Protective Effectiveness in the Mouse Model

Antibodies to both infectious forms of vaccinia virus, the mature virion (MV) and the enveloped virion (EV), as well as cell-mediated immune response appear to be important for protection against smallpox. EV virus particles, although more labile and less numerous than MV, are important for dissemin...

Descripción completa

Detalles Bibliográficos
Autores principales: Meseda, Clement A., Campbell, Joseph, Kumar, Arunima, Garcia, Alonzo D., Merchlinsky, Michael, Weir, Jerry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681963/
https://www.ncbi.nlm.nih.gov/pubmed/23785523
http://dx.doi.org/10.1371/journal.pone.0067984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681963/
https://www.ncbi.nlm.nih.gov/pubmed/23785523
http://dx.doi.org/10.1371/journal.pone.0067984

Ejemplares similares