The Availability of a Functional Tumor Targeting T-Cell Repertoire Determines the Anti-Tumor Efficiency of Combination Therapy with Anti-CTLA-4 and Anti-4-1BB Antibodies

It has previously been found that combination therapy with anti-CTLA-4 and anti-4-1BB antibodies may enhance tumor immunity. However, this treatment is not efficient against all tumors, and it has been suggested that variations in tumor control may reflect differences in the immunogenicity of differ...

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Detalles Bibliográficos
Autores principales: Jensen, Benjamin A. H., Pedersen, Sara R., Christensen, Jan P., Thomsen, Allan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681965/
https://www.ncbi.nlm.nih.gov/pubmed/23785471
http://dx.doi.org/10.1371/journal.pone.0066081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681965/
https://www.ncbi.nlm.nih.gov/pubmed/23785471
http://dx.doi.org/10.1371/journal.pone.0066081

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