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Pancreatic α-Cell Specific Deletion of Mouse Arx Leads to α-Cell Identity Loss

The specification and differentiation of pancreatic endocrine cell populations (α-, β-, δ, PP- and ε-cells) is orchestrated by a combination of transcriptional regulators. In the pancreas, Aristaless-related homeobox gene (Arx) is expressed first in the endocrine progenitors and then restricted to g...

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Detalles Bibliográficos
Autores principales: Wilcox, Crystal L., Terry, Natalie A., Walp, Erik R., Lee, Randall A., May, Catherine Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681972/
https://www.ncbi.nlm.nih.gov/pubmed/23785486
http://dx.doi.org/10.1371/journal.pone.0066214