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Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate
The purpose of this study was to examine the anti-oxidative activity of pectin and other polysaccharides in order to develop a cosmeceutical base having anti-oxidative effects towards retinyl palmitate (RP). The anti-oxidative stabilizing effects of pectin and other polysaccharides on RP were evalua...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682079/ https://www.ncbi.nlm.nih.gov/pubmed/23776395 http://dx.doi.org/10.4196/kjpp.2013.17.3.197 |
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author | Ro, Jieun Kim, Yeongseok Kim, Hyeongmin Jang, Soung Baek Lee, Hyun Joo Chakma, Suharto Jeong, Ji Hoon Lee, Jaehwi |
author_facet | Ro, Jieun Kim, Yeongseok Kim, Hyeongmin Jang, Soung Baek Lee, Hyun Joo Chakma, Suharto Jeong, Ji Hoon Lee, Jaehwi |
author_sort | Ro, Jieun |
collection | PubMed |
description | The purpose of this study was to examine the anti-oxidative activity of pectin and other polysaccharides in order to develop a cosmeceutical base having anti-oxidative effects towards retinyl palmitate (RP). The anti-oxidative stabilizing effects of pectin and other polysaccharides on RP were evaluated by DPPH assay and then the stabilizing effect of pectin on RP was examined as a function of time. Among the polysaccharides we examined, pectin exhibited a considerably higher anti-oxidative activity, with an approximately 5-fold greater DPPH radical scavenging effect compared to other polysaccharides. The DPPH radical scavenging effect of pectin increased gradually with increasing concentrations of pectin. At two different RP concentrations, 0.01 and 0.1% in ethanol, addition of pectin improved the stability of RP in a concentration dependent manner. The stabilizing effect of pectin on RP was more effective for the lower concentration of RP (0.01%, v/v). Further, degradation of RP was reduced following the addition of pectin as measured over 8 hours. From the results obtained, it can be suggested that pectin may be a promising ingredient for cosmeceutical bases designed to stabilize RP or other pharmacological agents subject to degradation by oxidation. |
format | Online Article Text |
id | pubmed-3682079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Physiological Society and The Korean Society of Pharmacology |
record_format | MEDLINE/PubMed |
spelling | pubmed-36820792013-06-17 Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate Ro, Jieun Kim, Yeongseok Kim, Hyeongmin Jang, Soung Baek Lee, Hyun Joo Chakma, Suharto Jeong, Ji Hoon Lee, Jaehwi Korean J Physiol Pharmacol Original Article The purpose of this study was to examine the anti-oxidative activity of pectin and other polysaccharides in order to develop a cosmeceutical base having anti-oxidative effects towards retinyl palmitate (RP). The anti-oxidative stabilizing effects of pectin and other polysaccharides on RP were evaluated by DPPH assay and then the stabilizing effect of pectin on RP was examined as a function of time. Among the polysaccharides we examined, pectin exhibited a considerably higher anti-oxidative activity, with an approximately 5-fold greater DPPH radical scavenging effect compared to other polysaccharides. The DPPH radical scavenging effect of pectin increased gradually with increasing concentrations of pectin. At two different RP concentrations, 0.01 and 0.1% in ethanol, addition of pectin improved the stability of RP in a concentration dependent manner. The stabilizing effect of pectin on RP was more effective for the lower concentration of RP (0.01%, v/v). Further, degradation of RP was reduced following the addition of pectin as measured over 8 hours. From the results obtained, it can be suggested that pectin may be a promising ingredient for cosmeceutical bases designed to stabilize RP or other pharmacological agents subject to degradation by oxidation. The Korean Physiological Society and The Korean Society of Pharmacology 2013-06 2013-06-11 /pmc/articles/PMC3682079/ /pubmed/23776395 http://dx.doi.org/10.4196/kjpp.2013.17.3.197 Text en Copyright © 2013 The Korean Physiological Society and The Korean Society of Pharmacology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ro, Jieun Kim, Yeongseok Kim, Hyeongmin Jang, Soung Baek Lee, Hyun Joo Chakma, Suharto Jeong, Ji Hoon Lee, Jaehwi Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title | Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title_full | Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title_fullStr | Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title_full_unstemmed | Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title_short | Anti-Oxidative Activity of Pectin and Its Stabilizing Effect on Retinyl Palmitate |
title_sort | anti-oxidative activity of pectin and its stabilizing effect on retinyl palmitate |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682079/ https://www.ncbi.nlm.nih.gov/pubmed/23776395 http://dx.doi.org/10.4196/kjpp.2013.17.3.197 |
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