2-(4-Hydroxyphenyl)-5-(3-Hydroxypropenyl)-7-Methoxybenzofuran, a Novel Ailanthoidol Derivative, Exerts Anti-Inflammatory Effect through Downregulation of Mitogen-Activated Protein Kinase in Lipopolysaccharide-Treated RAW 264.7 Cells

We reported that ailanthoidol, a neolignan from Zanthoxylum ailanthoides and Salvia miltiorrhiza Bunge, inhibited inflammatory reactions by macrophages and protected mice from endotoxin shock. We examined the anti-inflammatory activity of six synthetic ailanthoidol derivatives (compounds 1-6). Among...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon Jin, Jun, Jong-Gab, Kim, Jin-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682082/
https://www.ncbi.nlm.nih.gov/pubmed/23776398
http://dx.doi.org/10.4196/kjpp.2013.17.3.217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682082/
https://www.ncbi.nlm.nih.gov/pubmed/23776398
http://dx.doi.org/10.4196/kjpp.2013.17.3.217

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