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Elevating local concentrations of GPIIb–IIIa antagonists counteracts platelet thrombus stability

Glycoprotein IIb–IIIa (GPIIb–IIIa) antagonists have the capacity to destabilize coronary thrombi and restore vessel patency. Antagonist concentration and residence time, which can be increased by local intracoronary (LIC) administration, and thrombus age may be key factors that influence thrombus st...

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Detalles Bibliográficos
Autores principales: Speich, Henry E., Furman, Ronit R., Lands, Lindsey T., Moodie, Geoffrey D., Jennings, Lisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682094/
https://www.ncbi.nlm.nih.gov/pubmed/23073747
http://dx.doi.org/10.1007/s11239-012-0814-7