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Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia

Schnurri-2 (Shn-2), an nuclear factor-κB site-binding protein, tightly binds to the enhancers of major histocompatibility complex class I genes and inflammatory cytokines, which have been shown to harbor common variant single-nucleotide polymorphisms associated with schizophrenia. Although genes rel...

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Detalles Bibliográficos
Autores principales: Takao, Keizo, Kobayashi, Katsunori, Hagihara, Hideo, Ohira, Koji, Shoji, Hirotaka, Hattori, Satoko, Koshimizu, Hisatsugu, Umemori, Juzoh, Toyama, Keiko, Nakamura, Hironori K, Kuroiwa, Mahomi, Maeda, Jun, Atsuzawa, Kimie, Esaki, Kayoko, Yamaguchi, Shun, Furuya, Shigeki, Takagi, Tsuyoshi, Walton, Noah M, Hayashi, Nobuhiro, Suzuki, Hidenori, Higuchi, Makoto, Usuda, Nobuteru, Suhara, Tetsuya, Nishi, Akinori, Matsumoto, Mitsuyuki, Ishii, Shunsuke, Miyakawa, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682135/
https://www.ncbi.nlm.nih.gov/pubmed/23389689
http://dx.doi.org/10.1038/npp.2013.38