Cargando…
Deficiency of Schnurri-2, an MHC Enhancer Binding Protein, Induces Mild Chronic Inflammation in the Brain and Confers Molecular, Neuronal, and Behavioral Phenotypes Related to Schizophrenia
Schnurri-2 (Shn-2), an nuclear factor-κB site-binding protein, tightly binds to the enhancers of major histocompatibility complex class I genes and inflammatory cytokines, which have been shown to harbor common variant single-nucleotide polymorphisms associated with schizophrenia. Although genes rel...
Autores principales: | Takao, Keizo, Kobayashi, Katsunori, Hagihara, Hideo, Ohira, Koji, Shoji, Hirotaka, Hattori, Satoko, Koshimizu, Hisatsugu, Umemori, Juzoh, Toyama, Keiko, Nakamura, Hironori K, Kuroiwa, Mahomi, Maeda, Jun, Atsuzawa, Kimie, Esaki, Kayoko, Yamaguchi, Shun, Furuya, Shigeki, Takagi, Tsuyoshi, Walton, Noah M, Hayashi, Nobuhiro, Suzuki, Hidenori, Higuchi, Makoto, Usuda, Nobuteru, Suhara, Tetsuya, Nishi, Akinori, Matsumoto, Mitsuyuki, Ishii, Shunsuke, Miyakawa, Tsuyoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682135/ https://www.ncbi.nlm.nih.gov/pubmed/23389689 http://dx.doi.org/10.1038/npp.2013.38 |
Ejemplares similares
-
Immature morphological properties in subcellular-scale structures in the dentate gyrus of Schnurri-2 knockout mice: a model for schizophrenia and intellectual disability
por: Nakao, Akito, et al.
Publicado: (2017) -
ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response
por: Umemori, Juzoh, et al.
Publicado: (2013) -
Comprehensive behavioral analysis and quantification of brain free amino acids of C57BL/6J congenic mice carrying the 1473G allele in tryptophan hydroxylase‐2
por: Koshimizu, Hisatsugu, et al.
Publicado: (2018) -
Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein
por: Hagihara, Hideo, et al.
Publicado: (2018) -
Attenuated bidirectional short-term synaptic plasticity in the dentate gyrus of Schnurri-2 knockout mice, a model of schizophrenia
por: Kobayashi, Katsunori, et al.
Publicado: (2018)