Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

The role of exosomes in cancer can be inferred from the observation that they transfer tumor cell derived genetic material and signaling proteins, resulting in e.g. increased tumor angiogenesis and metastasis. However, the membrane transport mechanisms and the signaling events involved in the uptake...

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Detalles Bibliográficos
Autores principales: Svensson, Katrin J., Christianson, Helena C., Wittrup, Anders, Bourseau-Guilmain, Erika, Lindqvist, Eva, Svensson, Lena M., Mörgelin, Matthias, Belting, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682571/
https://www.ncbi.nlm.nih.gov/pubmed/23653359
http://dx.doi.org/10.1074/jbc.M112.445403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682571/
https://www.ncbi.nlm.nih.gov/pubmed/23653359
http://dx.doi.org/10.1074/jbc.M112.445403

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