Cargando…
Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1
The role of exosomes in cancer can be inferred from the observation that they transfer tumor cell derived genetic material and signaling proteins, resulting in e.g. increased tumor angiogenesis and metastasis. However, the membrane transport mechanisms and the signaling events involved in the uptake...
Autores principales: | Svensson, Katrin J., Christianson, Helena C., Wittrup, Anders, Bourseau-Guilmain, Erika, Lindqvist, Eva, Svensson, Lena M., Mörgelin, Matthias, Belting, Mattias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682571/ https://www.ncbi.nlm.nih.gov/pubmed/23653359 http://dx.doi.org/10.1074/jbc.M112.445403 |
Ejemplares similares
-
Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
por: Bourseau-Guilmain, E., et al.
Publicado: (2016) -
Nanotubes, exosomes, and nucleic acid–binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease
por: Belting, Mattias, et al.
Publicado: (2008) -
Tumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity
por: Christianson, Helena C., et al.
Publicado: (2017) -
Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease
por: Cha, Seon-Heui, et al.
Publicado: (2015) -
Avian Reovirus σB Interacts with Caveolin-1 in Lipid Rafts during Dynamin-Dependent Caveolae-Mediated Endocytosis
por: Wang, Yuyang, et al.
Publicado: (2022)