Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

Missense mutations in LRRK2 (leucine-rich repeat kinase 2) are a major cause of PD (Parkinson's disease). Several antibodies against LRRK2 have been developed, but results using these polyclonal antibodies have varied widely leading to conflicting conclusions. To address this challenge, the Mic...

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Detalles Bibliográficos
Autores principales: Davies, Paul, Hinkle, Kelly M., Sukar, Nour N., Sepulveda, Bryan, Mesias, Roxana, Serrano, Geidy, Alessi, Dario R., Beach, Thomas G., Benson, Deanna L., White, Charles L., Cowell, Rita M., Das, Sonal S., West, Andrew B., Melrose, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682752/
https://www.ncbi.nlm.nih.gov/pubmed/23560750
http://dx.doi.org/10.1042/BJ20121742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682752/
https://www.ncbi.nlm.nih.gov/pubmed/23560750
http://dx.doi.org/10.1042/BJ20121742

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