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Structural and evolutionary adaptation of rhoptry kinases and pseudokinases, a family of coccidian virulence factors

BACKGROUND: The widespread protozoan parasite Toxoplasma gondii interferes with host cell functions by exporting the contents of a unique apical organelle, the rhoptry. Among the mix of secreted proteins are an expanded, lineage-specific family of protein kinases termed rhoptry kinases (ROPKs), seve...

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Detalles Bibliográficos
Autores principales: Talevich, Eric, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682881/
https://www.ncbi.nlm.nih.gov/pubmed/23742205
http://dx.doi.org/10.1186/1471-2148-13-117