A Computationally Designed Water-Soluble Variant of a G-Protein-Coupled Receptor: The Human Mu Opioid Receptor

G-protein-coupled receptors (GPCRs) play essential roles in various physiological processes, and are widely targeted by pharmaceutical drugs. Despite their importance, studying GPCRs has been problematic due to difficulties in isolating large quantities of these membrane proteins in forms that retai...

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Detalles Bibliográficos
Autores principales: Perez-Aguilar, Jose Manuel, Xi, Jin, Matsunaga, Felipe, Cui, Xu, Selling, Bernard, Saven, Jeffery G., Liu, Renyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682944/
https://www.ncbi.nlm.nih.gov/pubmed/23799068
http://dx.doi.org/10.1371/journal.pone.0066009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682944/
https://www.ncbi.nlm.nih.gov/pubmed/23799068
http://dx.doi.org/10.1371/journal.pone.0066009

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