Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening

High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein, is released into the circulation during sterile inflammation (e.g. arthritis, trauma) and circulatory shock. It participates in the pathogenesis of delayed inflammatory responses and organ dysfunction. While several molecules...

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Detalles Bibliográficos
Autores principales: Gerö, Domokos, Szoleczky, Petra, Módis, Katalin, Pribis, John P., Al-Abed, Yousef, Yang, Huan, Chevan, Sangeeta, Billiar, Timothy R., Tracey, Kevin J., Szabo, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682954/
https://www.ncbi.nlm.nih.gov/pubmed/23799067
http://dx.doi.org/10.1371/journal.pone.0065994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682954/
https://www.ncbi.nlm.nih.gov/pubmed/23799067
http://dx.doi.org/10.1371/journal.pone.0065994

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