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Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening
High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein, is released into the circulation during sterile inflammation (e.g. arthritis, trauma) and circulatory shock. It participates in the pathogenesis of delayed inflammatory responses and organ dysfunction. While several molecules...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682954/ https://www.ncbi.nlm.nih.gov/pubmed/23799067 http://dx.doi.org/10.1371/journal.pone.0065994 |