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Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-Mannose, High-Mannose, or Complex Type N-Glycans

Highly pathogenic avian influenza H5N1 viruses can result in poultry and occasionally in human mortality. A safe and effective H5N1 vaccine is urgently needed to reduce the pandemic potential. Hemagglutinin (HA), a major envelope protein accounting for approximately 80% of spikes in influenza virus,...

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Detalles Bibliográficos
Autores principales: Lin, Shih-Chang, Jan, Jia-Tsrong, Dionne, Ben, Butler, Michael, Huang, Ming-Hsi, Wu, Chung-Yi, Wong, Chi-Huey, Wu, Suh-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682957/
https://www.ncbi.nlm.nih.gov/pubmed/23799128
http://dx.doi.org/10.1371/journal.pone.0066719