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Different Immunity Elicited by Recombinant H5N1 Hemagglutinin Proteins Containing Pauci-Mannose, High-Mannose, or Complex Type N-Glycans
Highly pathogenic avian influenza H5N1 viruses can result in poultry and occasionally in human mortality. A safe and effective H5N1 vaccine is urgently needed to reduce the pandemic potential. Hemagglutinin (HA), a major envelope protein accounting for approximately 80% of spikes in influenza virus,...
Autores principales: | Lin, Shih-Chang, Jan, Jia-Tsrong, Dionne, Ben, Butler, Michael, Huang, Ming-Hsi, Wu, Chung-Yi, Wong, Chi-Huey, Wu, Suh-Chin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682957/ https://www.ncbi.nlm.nih.gov/pubmed/23799128 http://dx.doi.org/10.1371/journal.pone.0066719 |
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