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Eukaryotic Translation Elongation Factor 1-Alpha 1 Inhibits p53 and p73 Dependent Apoptosis and Chemotherapy Sensitivity

The p53 family of transcription factors is a key regulator of cell proliferation and death. In this report we identify the eukaryotic translation elongation factor 1-alpha 1 (eEF1A1) to be a novel p53 and p73 interacting protein. Previous studies have demonstrated that eEF1A1 has translation-indepen...

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Detalles Bibliográficos
Autores principales: Blanch, Alvaro, Robinson, Fiona, Watson, Ian R., Cheng, Lynn S., Irwin, Meredith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682968/
https://www.ncbi.nlm.nih.gov/pubmed/23799104
http://dx.doi.org/10.1371/journal.pone.0066436