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Uptake and Intracellular Trafficking of Superantigens in Dendritic Cells

Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to current paradigm, SAgs interact directly and simultaneously with T cell receptor (TCR) on the T cell and MHC class II (MHC-II) on t...

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Detalles Bibliográficos
Autores principales: Ganem, María B., De Marzi, Mauricio C., Fernández-Lynch, María J., Jancic, Carolina, Vermeulen, Mónica, Geffner, Jorge, Mariuzza, Roy A., Fernández, Marisa M., Malchiodi, Emilio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682983/
https://www.ncbi.nlm.nih.gov/pubmed/23799083
http://dx.doi.org/10.1371/journal.pone.0066244