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Tumor Endothelial Cell-Specific Drug Delivery System Using Apelin-Conjugated Liposomes

BACKGROUND: A drug delivery system specifically targeting endothelial cells (ECs) in tumors is required to prevent normal blood vessels from being damaged by angiogenesis inhibitors. The purpose of this study was to investigate whether apelin, a ligand for APJ expressed in ECs when angiogenesis is t...

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Detalles Bibliográficos
Autores principales: Kawahara, Hiroki, Naito, Hisamichi, Takara, Kazuhiro, Wakabayashi, Taku, Kidoya, Hiroyasu, Takakura, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682998/
https://www.ncbi.nlm.nih.gov/pubmed/23799018
http://dx.doi.org/10.1371/journal.pone.0065499