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Tumor Endothelial Cell-Specific Drug Delivery System Using Apelin-Conjugated Liposomes
BACKGROUND: A drug delivery system specifically targeting endothelial cells (ECs) in tumors is required to prevent normal blood vessels from being damaged by angiogenesis inhibitors. The purpose of this study was to investigate whether apelin, a ligand for APJ expressed in ECs when angiogenesis is t...
Autores principales: | Kawahara, Hiroki, Naito, Hisamichi, Takara, Kazuhiro, Wakabayashi, Taku, Kidoya, Hiroyasu, Takakura, Nobuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682998/ https://www.ncbi.nlm.nih.gov/pubmed/23799018 http://dx.doi.org/10.1371/journal.pone.0065499 |
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