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Interferon Regulatory Factor 1 Polymorphisms Previously Associated with Reduced HIV Susceptibility Have No Effect on HIV Disease Progression

INTRODUCTION: Interferon regulatory factor 1 (IRF1) is induced by HIV early in the infection process and serves two functions: transactivation of the HIV-1 genome and thus replication, and eliciting antiviral innate immune responses. We previously described three IRF1 polymorphisms that correlate wi...

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Detalles Bibliográficos
Autores principales: Sivro, Aida, McKinnon, Lyle R., Ji, Hezhao, Kimani, Joshua, Jaoko, Walter, Plummer, Francis A., Su, Ruey-Chyi, Ball, T. Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683001/
https://www.ncbi.nlm.nih.gov/pubmed/23799084
http://dx.doi.org/10.1371/journal.pone.0066253