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Profiling of Childhood Adversity-Associated DNA Methylation Changes in Alcoholic Patients and Healthy Controls

The increased vulnerability to alcohol dependence (AD) seen in individuals with childhood adversity (CA) may result in part from CA-induced epigenetic changes. To examine CA-associated DNA methylation changes in AD patients, we examined peripheral blood DNA methylation levels of 384 CpGs in promoter...

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Detalles Bibliográficos
Autores principales: Zhang, Huiping, Wang, Fan, Kranzler, Henry R., Zhao, Hongyu, Gelernter, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683055/
https://www.ncbi.nlm.nih.gov/pubmed/23799031
http://dx.doi.org/10.1371/journal.pone.0065648