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Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant

C. elegans PUD-1 and PUD-2, two proteins up-regulated in daf-2(loss-of-function) (PUD), are homologous 17-kD proteins with a large abundance increase in long-lived daf-2 mutant animals of reduced insulin signaling. In this study, we show that both PUD-1 and PUD-2 are abundantly expressed in the inte...

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Detalles Bibliográficos
Autores principales: Ding, Yue-He, Du, Yun-Guang, Luo, Shukun, Li, Yu-Xin, Li, Tie-Mei, Yoshina, Sawako, Wang, Xing, Klage, Karsten, Mitani, Shohei, Ye, Keqiong, Dong, Meng-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683130/
https://www.ncbi.nlm.nih.gov/pubmed/23799143
http://dx.doi.org/10.1371/journal.pone.0067158