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(11)C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

BACKGROUND: A recent study from our laboratory demonstrated that (11)C-LY2428703, a new positron emission tomographic radioligand for metabotropic glutamate receptor 1 (mGluR1), has promising in vitro properties and excellent in vivo performance for imaging rat brain. The present study evaluated (11...

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Detalles Bibliográficos
Autores principales: Zanotti-Fregonara, Paolo, Barth, Vanessa N, Zoghbi, Sami S, Liow, Jeih-San, Nisenbaum, Eric, Siuda, Edward, Gladding, Robert L, Rallis-Frutos, Denise, Morse, Cheryl, Tauscher, Johannes, Pike, Victor W, Innis, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683333/
https://www.ncbi.nlm.nih.gov/pubmed/23758896
http://dx.doi.org/10.1186/2191-219X-3-47