Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

Recent molecular studies have revealed that, even when derived from a seemingly homogenous population, individual cells can exhibit substantial differences in gene expression, protein levels, and phenotypic output(1–5), with important functional consequences(4,5). Existing studies of cellular hetero...

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Detalles Bibliográficos
Autores principales: Shalek, Alex K., Satija, Rahul, Adiconis, Xian, Gertner, Rona S., Gaublomme, Jellert T., Raychowdhury, Raktima, Schwartz, Schragi, Yosef, Nir, Malboeuf, Christine, Lu, Diana, Trombetta, John T., Gennert, Dave, Gnirke, Andreas, Goren, Alon, Hacohen, Nir, Levin, Joshua Z., Park, Hongkun, Regev, Aviv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683364/
https://www.ncbi.nlm.nih.gov/pubmed/23685454
http://dx.doi.org/10.1038/nature12172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683364/
https://www.ncbi.nlm.nih.gov/pubmed/23685454
http://dx.doi.org/10.1038/nature12172

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