Cargando…

Alteration of 11β-Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptor by Ethanol in Rat Liver and Mouse Hepatoma Cells

Alcohol is a potential risk factor of type 2 diabetes, but its underlying mechanism is unclear. To explore this issue, Wistar rats and mouse hepatoma cells (Hepa 1–6) were exposed to ethanol, 8 g·kg(−1) ·d(−1) for 3 months and 100 mM for 48 h, respectively. Glucose and insulin tolerance tests in viv...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Zhaojie, Bao, Xueying, Zhang, Ming, Wei, Shengnan, Chang, Wenguang, Li, Jing, Chen, Li, Nyomba, B. L. Grégoire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683472/
https://www.ncbi.nlm.nih.gov/pubmed/23819126
http://dx.doi.org/10.1155/2013/218102