Local Overexpression of Interleukin-11 in the Central Nervous System Limits Demyelination and Enhances Remyelination

Demyelination is one of the pathological hallmarks of multiple sclerosis (MS). To date, no therapy is available which directly potentiates endogenous remyelination. Interleukin-11 (IL-11), a member of the gp130 family of cytokines, is upregulated in MS lesions. Systemic IL-11 treatment was shown to...

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Detalles Bibliográficos
Autores principales: Maheshwari, Anurag, Janssens, Kris, Bogie, Jeroen, Van Den Haute, Chris, Struys, Tom, Lambrichts, Ivo, Baekelandt, Veerle, Stinissen, Piet, Hendriks, Jerome J. A., Slaets, Helena, Hellings, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683504/
https://www.ncbi.nlm.nih.gov/pubmed/23818742
http://dx.doi.org/10.1155/2013/685317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683504/
https://www.ncbi.nlm.nih.gov/pubmed/23818742
http://dx.doi.org/10.1155/2013/685317

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