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BID-induced structural changes in BAK promote apoptosis
The BCL-2 family protein BAK is responsible for mitochondrial outer membrane permeabilization (MOMP), which leads to apoptosis. The BCL-2 homology (BH) 3-only protein BID activates BAK to perform this function. We report the NMR solution structure of the human BID BH3–BAK complex, which identified t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683554/ https://www.ncbi.nlm.nih.gov/pubmed/23604079 http://dx.doi.org/10.1038/nsmb.2563 |