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Viral genome structures are optimal for capsid assembly

Understanding how virus capsids assemble around their nucleic acid (NA) genomes could promote efforts to block viral propagation or to reengineer capsids for gene therapy applications. We develop a coarse-grained model of capsid proteins and NAs with which we investigate assembly dynamics and thermo...

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Detalles Bibliográficos
Autores principales: Perlmutter, Jason D, Qiao, Cong, Hagan, Michael F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683802/
https://www.ncbi.nlm.nih.gov/pubmed/23795290
http://dx.doi.org/10.7554/eLife.00632