Cargando…

Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system

Step 2 catalysis of pre-mRNA splicing entails the excision of the intron and ligation of the 5′ and 3′ exons. The tasks of the splicing factors Prp16, Slu7, Prp18, and Prp22 in the formation of the step 2 active site of the spliceosome and in exon ligation, and the timing of their recruitment, remai...

Descripción completa

Detalles Bibliográficos
Autores principales: Ohrt, Thomas, Odenwälder, Peter, Dannenberg, Julia, Prior, Mira, Warkocki, Zbigniew, Schmitzová, Jana, Karaduman, Ramazan, Gregor, Ingo, Enderlein, Jörg, Fabrizio, Patrizia, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683925/
https://www.ncbi.nlm.nih.gov/pubmed/23685439
http://dx.doi.org/10.1261/rna.039024.113