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Loop–loop interaction in an adenine-sensing riboswitch: A molecular dynamics study

Riboswitches are mRNA-based molecules capable of controlling the expression of genes. They undergo conformational changes upon ligand binding, and as a result, they inhibit or promote the expression of the associated gene. The close connection between structural rearrangement and function makes a de...

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Detalles Bibliográficos
Autores principales: Allnér, Olof, Nilsson, Lennart, Villa, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683926/
https://www.ncbi.nlm.nih.gov/pubmed/23716711
http://dx.doi.org/10.1261/rna.037549.112