Overexpression of DOC-1R Inhibits Cell Cycle G1/S Transition by Repressing CDK2 Expression and Activation

DOC-1R (deleted in oral cancer-1 related) is a novel putative tumor suppressor. This study investigated DOC-1R antitumor activity and the underlying molecular mechanisms. Cell phenotypes were assessed using flow cytometry, BrdU incorporation and CDK2 kinase assays in DOC-1R overexpressing HeLa cells...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Liu, Xing, Gao, Jinlan, Shi, Xiuyan, Hu, Xihua, Wang, Shusen, Luo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683939/
https://www.ncbi.nlm.nih.gov/pubmed/23781148
http://dx.doi.org/10.7150/ijbs.5763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683939/
https://www.ncbi.nlm.nih.gov/pubmed/23781148
http://dx.doi.org/10.7150/ijbs.5763

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