Cargando…

Roles Nrf2 Plays in Myeloid Cells and Related Disorders

The Keap1-Nrf2 system protects animals from oxidative and electrophilic stresses. Nrf2 is a transcription factor that induces the expression of genes essential for detoxifying reactive oxygen species (ROS) and cytotoxic electrophiles. Keap1 is a stress sensor protein that binds to and ubiquitinates...

Descripción completa

Detalles Bibliográficos
Autores principales: Kobayashi, Eri, Suzuki, Takafumi, Yamamoto, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684031/
https://www.ncbi.nlm.nih.gov/pubmed/23819012
http://dx.doi.org/10.1155/2013/529219