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Electron counting and beam-induced motion correction enable near atomic resolution single particle cryoEM

In recent work with large high symmetry viruses, single particle electron cryomicroscopy (cryoEM) has reached the milestone of determining near atomic resolution structures by allowing direct fitting of atomic models into experimental density maps. However, achieving this goal with smaller particles...

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Detalles Bibliográficos
Autores principales: Li, Xueming, Mooney, Paul, Zheng, Shawn, Booth, Chris, Braunfeld, Michael B., Gubbens, Sander, Agard, David A., Cheng, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684049/
https://www.ncbi.nlm.nih.gov/pubmed/23644547
http://dx.doi.org/10.1038/nmeth.2472