The ETS-Domain Transcription Factor Elk-1 Regulates COX-2 Gene Expression and Inhibits Glucose-Stimulated Insulin Secretion in the Pancreatic β-Cell Line INS-1

Cyclooxygenase-2 (COX-2) expression is associated with many aspects of physiological and pathological conditions, including pancreatic β-cell dysfunction. Prostaglandin E2 (PGE2) production, as a consequence of COX-2 gene induction, has been reported to impair β-cell function. The molecular mechanis...

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Detalles Bibliográficos
Autores principales: Zhang, Xiong-Fei, Zhu, Yi, Liang, Wen-Biao, Zhang, Jing-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684088/
https://www.ncbi.nlm.nih.gov/pubmed/23818898
http://dx.doi.org/10.1155/2013/843462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684088/
https://www.ncbi.nlm.nih.gov/pubmed/23818898
http://dx.doi.org/10.1155/2013/843462

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