Human glutaminyl cyclase and bacterial zinc aminopeptidase share a common fold and active site

BACKGROUND: Glutaminyl cyclase (QC) forms the pyroglutamyl residue at the amino terminus of numerous secretory peptides and proteins. We previously proposed the mammalian QC has some features in common with zinc aminopeptidases. We now have generated a structural model for human QC based on the amin...

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Detalles Bibliográficos
Autores principales: Booth, Rachell E, Lovell, Simon C, Misquitta, Stephanie A, Bateman, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368447/
https://www.ncbi.nlm.nih.gov/pubmed/15028118
http://dx.doi.org/10.1186/1741-7007-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC368447/
https://www.ncbi.nlm.nih.gov/pubmed/15028118
http://dx.doi.org/10.1186/1741-7007-2-2

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