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Overexpression of RBBP6, Alone or Combined with Mutant TP53, Is Predictive of Poor Prognosis in Colon Cancer

Retinoblastoma binding protein 6 (RBBP6) plays an important role in chaperone-mediated ubiquitination and interacts with TP53 in carcinogenesis. However, the clinicopathologic significance of RBBP6 expression in colon cancer is unknown; in particular, the prognostic value of RBBP6 combined with TP53...

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Detalles Bibliográficos
Autores principales: Chen, Jian, Tang, Huamei, Wu, Zehua, Zhou, Chongzhi, Jiang, Tao, Xue, Yingming, Huang, Guoyu, Yan, Dongwang, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684577/
https://www.ncbi.nlm.nih.gov/pubmed/23799110
http://dx.doi.org/10.1371/journal.pone.0066524