Development of a Spontaneous Liver Disease Resembling Autoimmune Hepatitis in Mice Lacking Tyro3, Axl and Mer Receptor Tyrosine Kinases

Autoimmune hepatitis (AIH) is a severe type of chronic liver disease. The lack of appropriate animal models has resulted in a limited understanding regarding the etiology of AIH. Here, we demonstrated that mice deficient in Tyro3, Axl and Mer (TAM) receptor tyrosine kinases (RTKs) developed persiste...

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Detalles Bibliográficos
Autores principales: Qi, Nan, Liu, Peipei, Zhang, Yue, Wu, Hui, Chen, Yongmei, Han, Daishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684578/
https://www.ncbi.nlm.nih.gov/pubmed/23799121
http://dx.doi.org/10.1371/journal.pone.0066604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684578/
https://www.ncbi.nlm.nih.gov/pubmed/23799121
http://dx.doi.org/10.1371/journal.pone.0066604

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