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Development of a Spontaneous Liver Disease Resembling Autoimmune Hepatitis in Mice Lacking Tyro3, Axl and Mer Receptor Tyrosine Kinases
Autoimmune hepatitis (AIH) is a severe type of chronic liver disease. The lack of appropriate animal models has resulted in a limited understanding regarding the etiology of AIH. Here, we demonstrated that mice deficient in Tyro3, Axl and Mer (TAM) receptor tyrosine kinases (RTKs) developed persiste...
Autores principales: | Qi, Nan, Liu, Peipei, Zhang, Yue, Wu, Hui, Chen, Yongmei, Han, Daishu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684578/ https://www.ncbi.nlm.nih.gov/pubmed/23799121 http://dx.doi.org/10.1371/journal.pone.0066604 |
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