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Genetic Characterization of the Drosophila Birt-Hogg-Dubé Syndrome Gene
Folliculin (FLCN) is a conserved tumor suppressor gene whose loss is associated with the human Birt-Hogg-Dubé (BHD) syndrome. However, its molecular functions remain largely unknown. In this work, we generated a Drosophila BHD model through genomic deletion of the FLCN gene (DBHD(−)). The DBHD mutan...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684598/ https://www.ncbi.nlm.nih.gov/pubmed/23799055 http://dx.doi.org/10.1371/journal.pone.0065869 |