SNAI1-Mediated Epithelial-Mesenchymal Transition Confers Chemoresistance and Cellular Plasticity by Regulating Genes Involved in Cell Death and Stem Cell Maintenance

Tumor cells at the tumor margin lose epithelial properties and acquire features of mesenchymal cells, a process called epithelial-to-mesenchymal transition (EMT). Recently, features of EMT were shown to be linked to cells with tumor-founding capability, so-called cancer stem cells (CSCs). Inducers o...

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Detalles Bibliográficos
Autores principales: Lim, Soyoung, Becker, Astrid, Zimmer, Andreas, Lu, Jianrong, Buettner, Reinhard, Kirfel, Jutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684605/
https://www.ncbi.nlm.nih.gov/pubmed/23799116
http://dx.doi.org/10.1371/journal.pone.0066558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684605/
https://www.ncbi.nlm.nih.gov/pubmed/23799116
http://dx.doi.org/10.1371/journal.pone.0066558

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