Role of Electron Microscopy in the Diagnosis of Cadasil Syndrome: A Study of 32 Patients

BACKGROUND AND PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by NOTCH3 gene mutations that result in vascular smooth muscle cell (VSMC) degeneration. Its distinctive feature by electron microscopy (EM) is granular osmiophilic...

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Detalles Bibliográficos
Autores principales: Morroni, Manrico, Marzioni, Daniela, Ragno, Michele, Di Bella, Paolo, Cartechini, Elisabetta, Pianese, Luigi, Lorenzi, Teresa, Castellucci, Mario, Scarpelli, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684609/
https://www.ncbi.nlm.nih.gov/pubmed/23799017
http://dx.doi.org/10.1371/journal.pone.0065482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684609/
https://www.ncbi.nlm.nih.gov/pubmed/23799017
http://dx.doi.org/10.1371/journal.pone.0065482

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