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Celastrol Prevents Atherosclerosis via Inhibiting LOX-1 and Oxidative Stress

Celastrol is a triterpenoid compound extracted from the Chinese herb Tripterygium wilfordii Hook F. Previous research has revealed its anti-oxidant, anti-inflammatory, anti-cancer and immunosuppressive properties. Here, we investigated whether celastrol inhibits oxidized low-density lipoprotein (oxL...

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Detalles Bibliográficos
Autores principales: Gu, Lei, Bai, Wenli, Li, Sha, Zhang, Yuqing, Han, Yi, Gu, Yue, Meng, Guoliang, Xie, Liping, Wang, Jing, Xiao, Yujiao, Shan, Liyang, Zhou, Suming, Wei, Lei, Ferro, Albert, Ji, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684610/
https://www.ncbi.nlm.nih.gov/pubmed/23799016
http://dx.doi.org/10.1371/journal.pone.0065477