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Inhibiting PTEN Protects Hippocampal Neurons against Stretch Injury by Decreasing Membrane Translocation of AMPA Receptor GluR2 Subunit

The AMPA type of glutamate receptors (AMPARs)-mediated excitotoxicity is involved in the secondary neuronal death following traumatic brain injury (TBI). But the underlying cellular and molecular mechanisms remain unclear. In this study, the role of phosphatase and tensin homolog deleted on chromoso...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Wang, Li, Long, Zai-yun, Wu, Ya-min, Wan, Qi, Jiang, Jian-xin, Wang, Zheng-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684616/
https://www.ncbi.nlm.nih.gov/pubmed/23799014
http://dx.doi.org/10.1371/journal.pone.0065431