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Impaired innate interferon induction in severe therapy resistant atopic asthmatic children

Deficient type I interferon-β and type III interferon-λ induction by rhinoviruses has previously been reported in mild/moderate atopic asthmatic adults. No studies have yet investigated if this occurs in severe therapy resistant asthma (STRA). Here, we show that compared with non-allergic healthy co...

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Detalles Bibliográficos
Autores principales: Edwards, M R, Regamey, N, Vareille, M, Kieninger, E, Gupta, A, Shoemark, A, Saglani, S, Sykes, A, Macintyre, J, Davies, J, Bossley, C, Bush, A, Johnston, S L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684776/
https://www.ncbi.nlm.nih.gov/pubmed/23212197
http://dx.doi.org/10.1038/mi.2012.118