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The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity
The integral membrane-bound Nrf1 transcription factor fulfils important functions in maintaining cellular homeostasis and organ integrity, but how it is controlled vectorially is unknown. Herein, creative use of Gal4-based reporter assays with protease protection assays (GRAPPA), and double fluoresc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684815/ https://www.ncbi.nlm.nih.gov/pubmed/23774320 http://dx.doi.org/10.1038/srep02006 |