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An Escherichia coli Effector Protein Promotes Host Mutation via Depletion of DNA Mismatch Repair Proteins

Enteropathogenic Escherichia coli (EPEC) is an attaching and effacing (A/E) human pathogen that causes diarrhea during acute infection, and it can also sustain asymptomatic colonization. A/E E. coli depletes host cell DNA mismatch repair (MMR) proteins in colonic cell lines and has been detected in...

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Detalles Bibliográficos
Autores principales: Maddocks, Oliver David Kenneth, Scanlon, Karen Mary, Donnenberg, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684829/
https://www.ncbi.nlm.nih.gov/pubmed/23781066
http://dx.doi.org/10.1128/mBio.00152-13