Human Cytomegalovirus (HCMV) Glycoprotein gB Promotes Virus Entry In Trans Acting as the Viral Fusion Protein Rather than as a Receptor-Binding Protein

Human cytomegalovirus (HCMV) glycoproteins gB and gH/gL are both necessary and sufficient for cell-cell fusion. However, it is not clear what roles these glycoproteins play in virus entry, whether acting directly in membrane fusion or in binding receptors. With other herpesviruses, it appears that g...

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Detalles Bibliográficos
Autores principales: Wille, Paul T., Wisner, Todd W., Ryckman, Brent, Johnson, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685210/
https://www.ncbi.nlm.nih.gov/pubmed/23736286
http://dx.doi.org/10.1128/mBio.00332-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685210/
https://www.ncbi.nlm.nih.gov/pubmed/23736286
http://dx.doi.org/10.1128/mBio.00332-13

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