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Three-dimensional structure of recombinant type 1 inositol 1,4,5-trisphosphate receptor

IP(3)Rs (inositol 1,4,5-trisphosphate receptors) are the intracellular channels that mediate release of Ca(2+) from the endoplasmic reticulum in response to the many stimuli that evoke Ins(1,4,5)P(3) formation. We characterized and purified type 1 IP(3)R heterologously expressed in Sf9 insect cells,...

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Detalles Bibliográficos
Autores principales: Wolfram, Francis, Morris, Edward, Taylor, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685215/
https://www.ncbi.nlm.nih.gov/pubmed/20377523
http://dx.doi.org/10.1042/BJ20100143